In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette
نویسندگان
چکیده
منابع مشابه
In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette
Gene targeting allows precise tailoring of the mouse genome such that desired modifications can be introduced under precise temporal and spatial control. This can be achieved through the use of site-specific recombinases, which mediate deletion or inversion of genomic DNA flanked by recombinase-specific recognition sites, coupled with gene targeting to introduce the recombinase recognition site...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2008
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkn627